The Influence of Genetic Variations in the CD86 Gene on the Outcome after Allogeneic Hematopoietic Stem Cell Transplantation.

doi:10.1155/2018/3826989

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Article

The Influence of Genetic Variations in the CD86 Gene on the Outcome after Allogeneic Hematopoietic Stem Cell Transplantation.

Journal of immunology research - 1 Jan 2018

Karabon Lidia, Markiewicz Miroslaw, Chrobot Karolina, Dzierzak-Mietla Monika, Pawlak-Adamska Edyta, Partyka Anna, Koclega Anna, Kyrcz-Krzemien Slawomira, Frydecka Irena

Abstract excerpt

CD86 molecule is the ligand for both costimulatory (CD28) and coinhibitory (CTLA-4) molecules, and it regulates immune response after allogeneic hematopoietic stem cell transplantation (alloHSCT). Therefore, we postulate that CD86 gene variations might influence the outcome after alloHSCT. Altogether, 295 adult patients (pts) undergoing related (105 pts) and unrelated (190 pts) donor-matched HSCT were genotyped...

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Identifiers

PMID: 29577049
DOI: 10.1155/2018/3826989
PMCID: PMC5821961

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.