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Short Communication: Characterization of a New HIV-1 Group N Isolate Originating from a Cameroonian Patient.

AIDS research and human retroviruses - 1 Jul 2018

Tagnouokam Ngoupo Paul Alain, Sadeuh-Mba Serge Alain, De Oliveira Fabienne, Ngo-Malabo Elodie Téclaire, Ngono Laure, Plantier Jean-Christophe, Kfutwah Anfumbom, Njouom Richard

Abstract excerpt

HIV-1 group N (HIV-1/N) remains rare and mainly restricted to Cameroon. In this study, we report a new HIV-1/N infected case identified during routine HIV screening activities in Yaounde. The genetic characterization of the near full-length genome of this virus strain revealed that it is genetically distinct to all HIV-1/N described to date. However, the Vpu protein responsible for tetherin antagonism displayed...

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PMID: 29575910
DOI: 10.1089/AID.2018.0015

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