Clonal interference can cause wavelet-like oscillations of multilocus linkage disequilibrium.

doi:10.1098/rsif.2017.0921

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Article

Clonal interference can cause wavelet-like oscillations of multilocus linkage disequilibrium.

Journal of the Royal Society, Interface - 1 Mar 2018

Garcia Victor, Glassberg Emily C, Harpak Arbel, Feldman Marcus W

Abstract excerpt

Within-host adaptation of pathogens such as human immunodeficiency virus (HIV) often occurs at more than two loci. Multiple beneficial mutations may arise simultaneously on different genetic backgrounds and interfere, affecting each other's fixation trajectories. Here, we explore how these evolutionary dynamics are mirrored in multilocus linkage disequilibrium (MLD), a measure of multi-way associations between...

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Identifiers

PMID: 29563246
DOI: 10.1098/rsif.2017.0921
PMCID: PMC5908532

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.