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Article

Cereblon loss and up-regulation of c-Myc are associated with lenalidomide resistance in multiple myeloma patients

15 Mar 2018

Abstract excerpt

Multiple myeloma (MM) patients who become refractory to anti-MM drugs have a very poor prognosis. Therefore, it is important to gain insight into the mechanisms of resistance to these drugs. Immunomodulatory drugs (IMiDs) have immune-stimulatory and anti-angiogenic properties as well as direct anti-

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PMID: 29545338
DOI: 10.3324/haematol.2017.186601

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Cereblon loss and up-regulation of c-Myc are associated with lenalidomide resistance in multiple myeloma patientsPMID 29545338Read ↗

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