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Article

Characterisation of mesenchymal stem cells from patients with amyotrophic lateral sclerosis.

Journal of clinical pathology - 1 Aug 2018

Matejckova Nicole, Zajicova Alena, Hermankova Barbora, Kossl Jan, Bohacova Pavla, Holan Vladimir, Javorkova Eliska

Abstract excerpt

AIMS: Mesenchymal stem cells (MSCs) have recently been tested in clinical trials to treat severe diseases, including amyotrophic lateral sclerosis (ALS). Since autologous MSCs are frequently used for therapy, we aimed to evaluate the possible influence of the disease on characteristics and function of these cells. METHODS: MSCs were isolated from the bone marrow of patients with ALS and compared with MSCs from...

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PMID: 29523587
DOI: 10.1136/jclinpath-2017-204681

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