Genotypic analysis of clinical and environmental Cryptococcus neoformans isolates from Brazil reveals the presence of VNB isolates and a correlation with biological factors.

doi:10.1371/journal.pone.0193237

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Article

Genotypic analysis of clinical and environmental Cryptococcus neoformans isolates from Brazil reveals the presence of VNB isolates and a correlation with biological factors.

PloS one - 1 Jan 2018

Andrade-Silva Leonardo Euripedes, Ferreira-Paim Kennio, Ferreira Thatiana Bragine, Vilas-Boas Anderson, Mora Delio José, Manzato Verônica Morais, Fonseca Fernanda Machado, Buosi Kelli, Andrade-Silva Juliana, Prudente Bruno da Silva, Araujo Natalia Evelyn, Sales-Campos Helioswilton, da Silva Marcus Vinicius, Júnior Virmondes Rodrigues, Meyer Wieland, Silva-Vergara Mario Léon

Abstract excerpt

Cryptococcal infections are mainly caused by members of the Cryptococcus neoformans species complex (molecular types VNI, VNII, VNB, VNIV and the AD hybrid VNIII). PCR of the mating type loci and MLST typing using the ISHAM-MLST consensus scheme were used to evaluate the genetic relationship of 102 (63 clinical and 39 environmental) C. neoformans isolates from Uberaba, Brazil and to correlate the obtained...

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PMID: 29505557
DOI: 10.1371/journal.pone.0193237
PMCID: PMC5837091

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