Article
Role of a single noncoding nucleotide in the evolution of an epidemic African clade of Salmonella.
Proceedings of the National Academy of Sciences of the United States of America - 13 Mar 2018
Hammarlöf Disa L, Kröger Carsten, Owen Siân V, Canals Rocío, Lacharme-Lora Lizeth, Wenner Nicolas, Schager Anna E, Wells Timothy J, Henderson Ian R, Wigley Paul, Hokamp Karsten, Feasey Nicholas A, Gordon Melita A, Hinton Jay C D
Abstract excerpt
Salmonella enterica serovar Typhimurium ST313 is a relatively newly emerged sequence type that is causing a devastating epidemic of bloodstream infections across sub-Saharan Africa. Analysis of hundreds of Salmonella genomes has revealed that ST313 is closely related to the ST19 group of S Typhimurium that cause gastroenteritis across the world. The core genomes of ST313 and ST19 vary by only ∼1,000 SNPs. We...
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