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Article

Microvesicles containing microRNA-21 secreted by proximal tubular epithelial cells are involved in renal interstitial fibrosis by activating AKT pathway.

European review for medical and pharmacological sciences - 1 Feb 2018

Zheng S-B, Zheng Y, Jin L-W, Zhou Z-H, Li Z-Y

Abstract excerpt

OBJECTIVE: To investigate the role of microvesicles containing microRNA-21 in renal interstitial fibrosis and its possible mechanism. MATERIALS AND METHODS: The renal interstitial fibrosis model was established by unilateral ureteral obstruction, and proximal tubule epithelial cell line (NRK52E) was used for cell model. The phenotype changes of the microvesicles containing microRNA-21 secreted by tubule cells...

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Share to Epithelial Cells
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Kidney Tubules

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Share to TOR Serine-Threonine Kinases

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Source

Identifiers

PMID: 29461599
DOI: 10.26355/eurrev_201802_14297

Genes

PTEN

Provenance

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