Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Distinct methylation profile of mucinous ovarian carcinoma reveals susceptibility to proteasome inhibitors

16 Feb 2018

Abstract excerpt

Mucinous type of epithelial ovarian cancer (MuOC) is a unique subtype with a poor survival outcome in recurrent and advanced stages. The role of type-specific epigenomics and its clinical significance remains uncertain. We analyzed the methylomic profiles of 6 benign mucinous adenomas, 24 MuOCs, 103 serous type of epithelial ovarian cancers (SeOCs) and 337 nonepithelial ovarian cancers. MuOC and SeOC exhibited...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Mechanisms and Therapy
Share to Epigenetics and DNA Methylation
Share to Ovarian cancer diagnosis and treatment

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 29451304
DOI: 10.1002/ijc.31324

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Distinct methylation profile of mucinous ovarian carcinoma reveals susceptibility to proteasome inhibitorsPMID 29451304Read ↗

The genomic landscape of carcinomas with mucinous differentiationSemantic proximity Read ↗

Molecular Subtyping of Serous Ovarian Cancer Based on Multi-omics DataSemantic proximity Read ↗

Genomic, Transcriptomic, Epigenetic, and Immune Profiling of Mucinous Breast CancerSemantic proximity Read ↗

The molecular background of mucinous carcinoma beyond MUC2Semantic proximity Read ↗

Multiomics Characterization of Low-Grade Serous Ovarian Carcinoma Identifies Potential Biomarkers of MEK Inhibitor Sensitivity and Therapeutic VulnerabilitySemantic proximity Read ↗

PSMD8 can serve as potential biomarker and therapeutic target of the PSMD family based on bioinformatics analysis and in vitro validationSemantic proximity Read ↗

Pan-cancer analysis of genomic and transcriptomic data reveals the prognostic relevance of human proteasome genes in different cancer typesSemantic proximity Read ↗

METTL2B m3C RNA Transferase: Oncogenic Role in Ovarian Cancer Progression and its Link to the Tumor Immune MicroenvironmentSemantic proximity Read ↗

Applications of Proteomics in Ovarian Cancer: Dawn of a New EraSemantic proximity Read ↗

A novel biomarker, MRPS12 functions as a potential oncogene in ovarian cancer and is a promising prognostic candidateSemantic proximity Read ↗

Perturbation of Rb, p53, and Brca1 or Brca2 cooperate in inducing metastatic serous epithelial ovarian cancer.Semantic proximity Read ↗

Expression and DNA methylation of 20S proteasome subunits as prognostic and resistance markers in cancerSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.