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Article

Retreatment with sofosbuvir/velpatasvir in cirrhotic patients with genotype-4 who failed a previous interferon-free regimen: a case series.

Antiviral therapy - 1 Jan 2018

Boglione Lucio, Pinna Simone Mornese, Lupia Tommaso, Cariti Giuseppe, Di Perri Giovanni

Abstract excerpt

BACKGROUND: The novel available interferon (IFN)-free regimens significantly improved the sustained virological response (SVR) in patients with chronic hepatitis C (CHC), without important side effects and with shorter duration of treatment. In a subset of patients, however, the treatment failure (TF) was due to the presence of resistance-associated substitutions (RAS) that lead to virological breakthrough (BT)...

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Identifiers

PMID: 29442067
DOI: 10.3851/IMP3226

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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