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Article

Mutations in OTOF, CLDN14 & SLC26A4 genes as major causes of hearing impairment in Dhadkai village, Jammu & Kashmir, India.

The Indian journal of medical research - 1 Oct 2017

Pandey Nishtha, Rashid Tabassum, Jalvi Rajeev, Sharma Meenakshi, Rangasayee Raghunath, Andrabi Khurshid Iqbal, Anand Anuranjan

Abstract excerpt

Background & objectives: A high incidence of hearing impairment is reported from the village of Dhadkai in the State of Jammu and Kashmir, India. Prevalence of endogamy in this community suggested a common genetic basis for the disorder. A genetic study was undertaken to ascertain the basis for the high incidence of hearing impairment in this region. Methods: In a two-step approach to identify the causative...

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Source

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Identifiers

PMID: 29434063
DOI: 10.4103/ijmr.IJMR_635_15
PMCID: PMC5819031

Genes

CLDN14
OTOF
TMC1
TMIE
TMPRSS3

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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