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Article

Swinepox virus vector-based vaccines: attenuation and biosafety assessments following subcutaneous prick inoculation.

Veterinary research - 7 Feb 2018

Yuan Xiaomin, Lin Huixing, Li Bin, He Kongwang, Fan Hongjie

Abstract excerpt

Swinepox virus (SPV) has several advantages as a potential clinical vector for a live vector vaccine. In this study, to obtain a safer and more efficient SPV vector, three SPV mutants, Δ003, Δ010, and ΔTK were successfully constructed. A virus replication experiment showed that these SPV mutants had lower replication abilities compared to wtSPV in 10 different host-derived cell lines. Animal experiments with...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 29415767
DOI: 10.1186/s13567-018-0510-5
PMCID: PMC5804073

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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