Article
Association between α1-antitrypsin and bronchiectasis in patients with humoral immunodeficiency receiving gammaglobulin infusions.
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology - 1 Feb 2018
Peppers Brian P, Zacharias Jamie, Michaud Chelsea R, Frith John A, Varma Priya, Henning Mark, Quinn Linda M, Tcheurekdjian Haig, Craig Timothy, Hostoffer Robert W
Abstract excerpt
BACKGROUND: In patients with humoral immunodeficiency, the progression of bronchiectasis has been known to occur despite adequate gammaglobulin therapy and in the absence of recurrent infections. This observation suggests that factors other than gammaglobulin replacement might play a part in the prevention of lung damage in this population. α1-Antitrypsin deficiency can be associated with bronchiectasis, a...
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