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Article

Ancestral Variations of the PCDHG Gene Cluster Predispose to Dyslexia in a Multiplex Family.

EBioMedicine - 1 Feb 2018

Naskar Teesta, Faruq Mohammed, Banerjee Priyajit, Khan Massarat, Midha Rashi, Kumari Renu, Devasenapathy Subhashree, Prajapati Bharat, Sengupta Sanghamitra, Jain Deepti, Mukerji Mitali, Singh Nandini Chatterjee, Sinha Subrata

Abstract excerpt

Dyslexia is a heritable neurodevelopmental disorder characterized by difficulties in reading and writing. In this study, we describe the identification of a set of 17 polymorphisms located across 1.9Mb region on chromosome 5q31.3, encompassing genes of the PCDHG cluster, TAF7, PCDH1 and ARHGAP26, dominantly inherited with dyslexia in a multi-incident family. Strikingly, the non-risk form of seven variations of...

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Source

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Identifiers

PMID: 29409727
DOI: 10.1016/j.ebiom.2017.12.031
PMCID: PMC5835549

Genes

ARHGAP26
PCDH1
TAF7

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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