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In vitro follicle growth supports human oocyte meiotic maturation

27 Nov 2015

Abstract excerpt

In vitro follicle growth is a potential approach to preserve fertility for young women who are facing a risk of premature ovarian failure (POF) caused by radiation or chemotherapy. Our two-step follicle culture strategy recapitulated the dynamic human follicle growth environment in vitro. Follicles developed from the preantral to antral stage, and, for the first time, produced meiotically competent metaphase II...

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PMID: 26612176
DOI: 10.1038/srep17323

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