Article
Primary failure of eruption: Clinical and genetic findings in the mixed dentition.
The Angle orthodontist - 1 May 2018
Grippaudo Cristina, Cafiero Concetta, D'Apolito Isabella, Ricci Beatrice, Frazier-Bowers Sylvia A
Abstract excerpt
OBJECTIVE: To test the hypothesis that mutations in the parathyroid hormone 1 receptor ( PTH1R) include effects in both primary and permanent teeth. MATERIALS AND METHODS: DNA was extracted from saliva samples of 29 patients (8 familial and 21 sporadic) who presented with clinical evidence of infraoccluded teeth, and their unaffected relatives (N = 22). Sequencing followed by mutational analysis of the coding...
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