Article
Anti-NT5C1A autoantibodies are associated with more severe disease in patients with juvenile myositis.
Annals of the rheumatic diseases - 1 May 2018
Yeker Richard M, Pinal-Fernandez Iago, Kishi Takayuki, Pak Katherine, Targoff Ira N, Miller Frederick W, Rider Lisa G, Mammen Andrew L
Abstract excerpt
OBJECTIVES: Autoantibodies recognising cytosolic 5'-nucleotidase 1A (NT5C1A) are found in adult patients with myositis and other autoimmune diseases. They are especially prevalent in adults with inclusion body myositis (IBM), in which they are associated with more severe weakness and higher mortality. This study was undertaken to define the prevalence and clinical features associated with anti-NT5C1A...
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