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Article

Chemical hijacking of auxin signaling with an engineered auxin-TIR1 pair.

Nature chemical biology - 1 Mar 2018

Uchida Naoyuki, Takahashi Koji, Iwasaki Rie, Yamada Ryotaro, Yoshimura Masahiko, Endo Takaho A, Kimura Seisuke, Zhang Hua, Nomoto Mika, Tada Yasuomi, Kinoshita Toshinori, Itami Kenichiro, Hagihara Shinya, Torii Keiko U

Abstract excerpt

The phytohormone auxin indole-3-acetic acid (IAA) regulates nearly all aspects of plant growth and development. Despite substantial progress in our understanding of auxin biology, delineating specific auxin response remains a major challenge. Auxin regulates transcriptional response via its receptors, TIR1 and AFB F-box proteins. Here we report an engineered, orthogonal auxin-TIR1 receptor pair, developed through...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 29355850
DOI: 10.1038/nchembio.2555
PMCID: PMC5812785

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