Article
The rise of a novel classification system for endometrial carcinoma; integration of molecular subclasses.
The Journal of pathology - 1 Apr 2018
McAlpine Jessica, Leon-Castillo Alicia, Bosse Tjalling
Abstract excerpt
Endometrial cancer is a clinically heterogeneous disease and it is becoming increasingly clear that this heterogeneity may be a function of the diversity of the underlying molecular alterations. Recent large-scale genomic studies have revealed that endometrial cancer can be divided into at least four distinct molecular subtypes, with well-described underlying genomic aberrations. These subtypes can be reliably...
Topics
- Biomarkers, Tumor
- Carcinoma
- Clinical Decision-Making
- Databases, Genetic
- Endometrial Neoplasms
- Female
- Genetic Predisposition to Disease
- Genome, Human
- Genomics
- Humans
- Pathology, Molecular
