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CRISPR-Cas Targeting of Host Genes as an Antiviral Strategy

16 Jan 2018

Abstract excerpt

Currently, a new gene editing tool-the Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) associated (Cas) system-is becoming a promising approach for genetic manipulation at the genomic level. This simple method, originating from the adaptive immune defense system in prokaryotes, has been developed and applied to antiviral research in humans. Based on the characteristics of virus-host...

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PMID: 29337866
DOI: 10.3390/v10010040

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