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Article

DICER1 gene mutations in endocrine tumors.

Endocrine-related cancer - 1 Mar 2018

Solarski Michael, Rotondo Fabio, Foulkes William D, Priest John R, Syro Luis V, Butz Henriett, Cusimano Michael D, Kovacs Kalman

Abstract excerpt

In this review, the importance of the DICER1 gene in the function of endocrine cells is discussed. There is conclusive evidence that DICER1 mutations play a crucial role in the development, progression, cell proliferation, therapeutic responsiveness and behavior of several endocrine tumors. We review the literature of DICER1 gene mutations in thyroid, parathyroid, pituitary, pineal gland, endocrine pancreas,...

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Identifiers

PMID: 29330195
DOI: 10.1530/ERC-17-0509

Genes

DICER1

Provenance

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