Article
Systematic review with meta-analysis: effectiveness and tolerability of interferon-free direct-acting antiviral regimens for chronic hepatitis C genotype 1 in routine clinical practice in Asia.
Alimentary pharmacology & therapeutics - 1 Mar 2018
Ji F, Wei B, Yeo Y H, Ogawa E, Zou B, Stave C D, Li Z, Dang S, Furusyo N, Cheung R C, Nguyen M H
Abstract excerpt
BACKGROUND: Direct-acting antiviral (DAA) regimens have shown high efficacy and tolerability for patients with HCV genotype 1/1b (GT1/1b) in clinical trials. However, robust real-world evidence of interferon (IFN)-free DAA treatment for HCV GT1-infected patients in Asia is still lacking. AIM: To systematically review and meta-analyse the effectiveness and tolerability of IFN-free DAA therapy for HCV GT1 infection...
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