Effectiveness, safety and clinical outcomes of direct-acting antiviral therapy in HCV genotype 1 infection: Results from a Spanish real-world cohort.

doi:10.1016/j.jhep.2017.01.028

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Article

Effectiveness, safety and clinical outcomes of direct-acting antiviral therapy in HCV genotype 1 infection: Results from a Spanish real-world cohort.

Journal of hepatology - 1 Jun 2017

Calleja Jose Luis, Crespo Javier, Rincón Diego, Ruiz-Antorán Belén, Fernandez Inmaculada, Perelló Christie, Gea Francisco, Lens Sabela, García-Samaniego Javier, Sacristán Begoña, García-Eliz María, Llerena Susana, Pascasio Juan Manuel, Turnes Juan, Torras Xavier, Morillas Rosa Maria, Llaneras Jordi, Serra Miguel A, Diago Moises, Rodriguez Conrado Fernández, Ampuero Javier, Jorquera Francisco, Simon Miguel A, Arenas Juan, Navascues Carmen Alvarez, Bañares Rafael, Muñoz Raquel, Albillos Agustin, Mariño Zoe

Abstract excerpt

BACKGROUND & AIMS: Clinical trials evaluating second-generation direct-acting antiviral agents (DAAs) have shown excellent rates of sustained virologic response (SVR) and good safety profiles in patients with chronic hepatitis C virus (HCV) genotype 1 infection. We aimed to investigate the effectiveness and safety of two oral DAA combination regimens, ombitasvir/paritaprevir/ritonavir plus dasabuvir...

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PMID: 28189751
DOI: 10.1016/j.jhep.2017.01.028

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