Autosomal dominant cerebellar ataxias: clinical features, genetics, and pathogenesis.

Abstract excerpt

Autosomal dominant cerebellar ataxias are hereditary neurodegenerative disorders that are known as spinocerebellar ataxias (SCA) in genetic nomenclature. In the pregenomic era, ataxias were some of the most poorly understood neurological disorders; the unravelling of their molecular basis enabled precise diagnosis in vivo and explained many clinical phenomena such as anticipation and variable phenotypes even...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Cell Death
• Share to Diagnostic Imaging
• Share to Electrophysiology