Reappraisal of Morphologic Differences Between Renal Medullary Carcinoma, Collecting Duct Carcinoma, and Fumarate Hydratase-deficient Renal Cell Carcinoma.

doi:10.1097/PAS.0000000000001000

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Article

Reappraisal of Morphologic Differences Between Renal Medullary Carcinoma, Collecting Duct Carcinoma, and Fumarate Hydratase-deficient Renal Cell Carcinoma.

The American journal of surgical pathology - 1 Mar 2018

Ohe Chisato, Smith Steven C, Sirohi Deepika, Divatia Mukul, de Peralta-Venturina Mariza, Paner Gladell P, Agaimy Abbas, Amin Mitual B, Argani Pedram, Chen Ying-Bei, Cheng Liang, Colecchia Maurizio, Compérat Eva, Werneck da Cunha Isabela, Epstein Jonathan I, Gill Anthony J, Hes Ondřej, Hirsch Michelle S, Jochum Wolfram, Kunju Lakshmi P, Maclean Fiona, Magi-Galluzzi Cristina, McKenney Jesse K, Mehra Rohit, Nesi Gabriella, Osunkoya Adeboye O, Picken Maria M, Rao Priya, Reuter Victor E, de Oliveira Salles Paulo Guilherme, Schultz Luciana, Tickoo Satish K, Tomlins Scott A, Trpkov Kiril, Amin Mahul B

Abstract excerpt

Renal medullary carcinomas (RMCs) and collecting duct carcinomas (CDCs) are rare subsets of lethal high-stage, high-grade distal nephron-related adenocarcinomas with a predilection for the renal medullary region. Recent findings have established an emerging group of fumarate hydratase (FH)-deficient tumors related to hereditary leiomyomatosis and renal cell carcinoma (HLRCC-RCCs) syndrome within this morphologic...

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PMID: 29309300
DOI: 10.1097/PAS.0000000000001000
PMCID: PMC8015937

Genes

SMARCB1

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