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Article

Colorectal cancer specific conditions promote Streptococcus gallolyticus gut colonization

26 Dec 2017

Abstract excerpt

Significance Growing evidence indicates a correlation between colorectal cancer and intestinal dysbiosis or colonization by single bacterial species such as Streptococcus gallolyticus subsp. gallolyticus (SGG), yet a causality link remains to be established. To address this point experimentally, we colonized Apc +/ − Notch-inducible mice with SGG. Apc +/ − is a pioneer somatic mutation driving the occurrence of...

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PMID: 29279402
DOI: 10.1073/pnas.1715112115

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