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Article

The function and evolutionary significance of a triplicated Na,K-ATPase gene in a toxin-specialized insect.

BMC evolutionary biology - 15 Dec 2017

Lohr Jennifer N, Meinzer Fee, Dalla Safaa, Romey-Glüsing Renja, Dobler Susanne

Abstract excerpt

BACKGROUND: The Na,K-ATPase is a vital animal cell-membrane protein that maintains the cell's resting potential, among other functions. Cardenolides, a group of potent plant toxins, bind to and inhibit this pump. The gene encoding the α-subunit of the pump has undergone duplication events in some insect species known to feed on plants containing cardenolides. Here we test the function of these duplicated gene...

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Identifiers

PMID: 29246105
DOI: 10.1186/s12862-017-1097-6
PMCID: PMC5732401

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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