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Article

Microorganisms in the human placenta are associated with altered CpG methylation of immune and inflammation-related genes

14 Dec 2017

Abstract excerpt

Microorganisms in the placenta have been linked to adverse pregnancy outcomes as well as neonatal illness. Inflammation in the placenta has been identified as a contributing factor in this association, but the underlying biological mechanisms are not yet fully understood. The placental epigenome may serve as an intermediate between placental microbes and inflammation, contributing to adverse outcomes in the...

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PMID: 29240761
DOI: 10.1371/journal.pone.0188664

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