Article
Immune response profiling of primary monocytes and oral keratinocytes to different Tannerella forsythia strains and their cell surface mutants.
Molecular oral microbiology - 1 Apr 2018
Bloch S, Zwicker S, Bostanci N, Sjöling Å, Boström E A, Belibasakis G N, Schäffer C
Abstract excerpt
The oral pathogen Tannerella forsythia possesses a unique surface (S-) layer with a complex O-glycan containing a bacterial sialic acid mimic in the form of either pseudaminic acid or legionaminic acid at its terminal position. We hypothesize that different T. forsythia strains employ these stereoisomeric sugar acids for interacting with the immune system and resident host tissues in the periodontium. Here, we...
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