Article
Familial Association of Granulocyte-Macrophage Colony-Stimulating Factor Autoantibodies in Inflammatory Bowel Disease.
Journal of pediatric gastroenterology and nutrition - 1 May 2018
Wright Sandra S, Trauernicht Anna, Bonkowski Erin, McCall Courtney A, Maier Elizabeth A, Bezold Ramona, Lake Kathleen, Chalk Claudia, Trapnell Bruce C, Kim Mi-Ok, Kugathasan Subra, Denson Lee A
Abstract excerpt
OBJECTIVES: Elevated granulocyte-macrophage colony-stimulating factor auto-antibodies (GM-CSF Ab) are associated with increased intestinal permeability and stricturing behavior in Crohn disease (CD). We tested for familial association of serum GM-CSF Ab level in CD and ulcerative colitis (UC) families. METHODS: Serum GM-CSF Ab concentration was determined in 230 pediatric CD probands and 404 of their unaffected...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.