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Article

Comparison of exercise training responses in COPD patients with and without Alpha-1 antitrypsin deficiency.

Respiratory medicine - 1 Sept 2017

Jarosch Inga, Hitzl Wolfgang, Koczulla Andreas Rembert, Wencker Marion, Welte Tobias, Gloeckl Rainer, Janciauskiene Sabina, Kenn Klaus

Abstract excerpt

BACKGROUND: The benefits of pulmonary rehabilitation (PR) on fatigue-resistant skeletal muscle fibre type I have been found to be smaller in COPD patients with alpha-1 antitrypsin deficiency (AATD) than in those without AATD. Alpha-1 antitrypsin (AAT) augmentation therapy was suggested as a potential factor of influence. Whether this finding mirrors different improvements in 6-min walk distance (6MWD) between...

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PMID: 29206641
DOI: 10.1016/j.rmed.2017.07.009

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