Article
Effects of simulated microgravity on gene expression and biological phenotypes of a single generation Caenorhabditis elegans cultured on 2 different media.
Life sciences in space research - 1 Nov 2017
Tee Ling Fei, Neoh Hui-Min, Then Sue Mian, Murad Nor Azian, Asillam Mohd Fairos, Hashim Mohd Helmy, Nathan Sheila, Jamal Rahman
Abstract excerpt
Studies of multigenerational Caenorhabditis elegans exposed to long-term spaceflight have revealed expression changes of genes involved in longevity, DNA repair, and locomotion. However, results from spaceflight experiments are difficult to reproduce as space missions are costly and opportunities are rather limited for researchers. In addition, multigenerational cultures of C. elegans used in previous studies...
Topics
- Animals
- Animals, Genetically Modified
- Caenorhabditis elegans
- Culture Media
- Locomotion
- Longevity
- Phenotype
- Reproduction
- Space Flight
- Transcriptome
- Weightlessness Simulation