Article
A novel cell-based high throughput assay to determine neutralizing antibody titers against circulating strains of rubella virus.
Journal of virological methods - 1 Feb 2018
Kanbayashi Daiki, Kurata Takako, Takahashi Kazuo, Kase Tetsuo, Komano Jun
Abstract excerpt
A large rubella outbreak occurred in Japan 2013, and 14,344 rubella and 45 congenital rubella syndrome (CRS) cases were reported. At that time, the populational immunity was above the protective threshold assessed by hemmaglutination inhibition (HI) titer. The genotype 2B rubella virus (RV) strains were responsible for the outbreak, which are non-indigenous in Japan. In this work, a cell-based high throughput...
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