Article
Identification of a novel linear B-cell epitope in nonstructural protein 11 of porcine reproductive and respiratory syndrome virus that are conserved in both genotypes.
PloS one - 1 Jan 2017
Jiang Nan, Jin Huan, Li Yi, Ge Xinna, Han Jun, Guo Xin, Zhou Lei, Yang Hanchun
Abstract excerpt
Porcine reproductive and respiratory syndrome virus (PRRSV) is one of the most economically important pathogens, that hinder the development of global pork industry. Its nonstructural protein 11 (nsp11), with the nidoviral uridylate-specific endoribonuclease (NendoU) domain, is essential for PRRSV genome replication and it also contributes to host innate immunity suppression. However, the immunogenicity and...
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