Article
The outer membrane protein OprF and the sigma factor SigX regulate antibiotic production in Pseudomonas fluorescens 2P24.
Microbiological research - 1 Jan 2018
Li Xu, Gu Gao-Qi, Chen Wei, Gao Li-Juan, Wu Xue-Hong, Zhang Li-Qun
Abstract excerpt
Pseudomonas fluorescens 2P24 produces 2,4-diacetylphloroglucinol (2,4-DAPG) as the major antibiotic compound that protects plants from soil-borne diseases. Expression of the 2,4-DAPG biosynthesis enzymes, which are encoded by the phlACBD locus, is under the control of a delicate regulatory network. In this study, we identified a novel role for the outer membrane protein gene oprF, in negatively regulating the...
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