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Article

Identification of duplication downstream of BMP2 in a Chinese family with brachydactyly type A2 (BDA2).

PloS one - 1 Jan 2014

Liu Xudong, Gao Linghan, Zhao Aman, Zhang Rui, Ji Baohu, Wang Lei, Zheng Yonglan, Zeng Bingfang, Valenzuela Robert K, He Lin, Ma Jie

Abstract excerpt

Brachydactyly type A2 (BDA2, MIM 112600) is characterized by the deviation and shortening of the middle phalange of the index finger and the second toe. Using genome-wide linkage analysis in a Chinese BDA2 family, we mapped the maximum candidate interval of BDA2 to a ∼1.5 Mb region between D20S194 and D20S115 within chromosome 20p12.3 and found that the pairwise logarithm of the odds score was highest for marker...

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Open in PubMed Open full text

Identifiers

PMID: 24710560
DOI: 10.1371/journal.pone.0094201
PMCID: PMC3978006

Genes

BMP2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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