Article
Analysis of circulating miRNAs in patients with familial hypercholesterolaemia treated by LDL/Lp(a) apheresis.
Atherosclerosis. Supplements - 1 Nov 2017
Dlouha Dana, Blaha Milan, Blaha Vladimir, Fatorova Ilona, Hubacek Jaroslav A, Stavek Petr, Lanska Vera, Parikova Alena, Pitha Jan
Abstract excerpt
BACKGROUND: LDL/Lp(a) apheresis therapy is a well-established method of aggressively lowering LDL and Lp(a). Recently, miRNAs have been discussed as markers of vascular status including atherosclerosis. MiRNAs inhibit post-transcriptional processes through RNA duplex formation resulting in gene silencing or regulation of gene expression. MATERIALS AND METHODS: We measured a profile of 175 plasma-circulating...
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