Emerging resistant clones of Mycobacterium tuberculosis in a spatiotemporal context.

doi:10.1093/jac/dkx372

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Article

Emerging resistant clones of Mycobacterium tuberculosis in a spatiotemporal context.

The Journal of antimicrobial chemotherapy - 1 Feb 2018

Vyazovaya Anna, Levina Klavdia, Zhuravlev Viacheslav, Viiklepp Piret, Kütt Marge, Mokrousov Igor

Abstract excerpt

Objectives: We assessed the genetic structure of the Mycobacterium tuberculosis population in Estonia with a special focus on major epidemic/endemic clones and drug resistance determinants. We investigated the hypothesis of the decisive impact of massive human influx on the locally circulating genotypes. Estonia received a mass immigration from Russia during 1945-90 followed by enhanced interaction with the EU...

Topics

Adult
Aged
Aged, 80 and over
Antitubercular Agents
Bacterial Proteins
Drug Resistance, Bacterial
Estonia
Female
Genotype
Genotyping Techniques
Humans
Male
Microbial Sensitivity Tests
Middle Aged
Mycobacterium tuberculosis
Prevalence
Spatio-Temporal Analysis
Tuberculosis, Multidrug-Resistant

Source

Open in PubMed

Identifiers

PMID: 29092043
DOI: 10.1093/jac/dkx372

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