Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Using DIVAN to assess disease/trait-associated single nucleotide variants in genome-wide scale.

BMC research notes - 30 Oct 2017

Chen Li, Qin Zhaohui S

Abstract excerpt

OBJECTIVE: The majority of sequence variants identified by Genome-wide association studies (GWASs) fall outside of the protein-coding regions. Unlike coding variants, it is challenging to connect these noncoding variants to the pathophysiology of complex diseases/traits due to the lack of functional annotations in the non-coding regions. To overcome this, by leveraging the rich collection of genomic and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genetic Variation
Share to Genome, Human
Share to Genome-Wide Association Study

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genomics

Share to Polymorphism, Single Nucleotide

Share to Software

Source

Open in PubMed Open full text

Identifiers

PMID: 29084591
DOI: 10.1186/s13104-017-2851-y
PMCID: PMC5663107

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Using DIVAN to assess disease/trait-associated single nucleotide variants in genome-wide scale.PMID 29084591Read ↗

DIVAN: accurate identification of non-coding disease-specific risk variants using multi-omics profiles.Semantic proximity Read ↗

NCAD v1.0: a database for non-coding variant annotation and interpretation.Semantic proximity Read ↗

DIVAS: a centralized genetic variant repository representing 150,000 individuals from multiple disease cohorts.Semantic proximity Read ↗

Current trend of annotating single nucleotide variation in humans--A case study on SNVrap.Semantic proximity Read ↗

Needles in stacks of needles: finding disease-causal variants in a wealth of genomic data.Semantic proximity Read ↗

Divine: Prioritizing Genes for Rare Mendelian Disease in Whole Exome Sequencing DataSemantic proximity Read ↗

SNPnexus: assessing the functional relevance of genetic variation to facilitate the promise of precision medicine.Semantic proximity Read ↗

Prediction of disease-associated functional variants in noncoding regions through a comprehensive analysis by integrating datasets and features.Semantic proximity Read ↗

VARAdb: a comprehensive variation annotation database for human.Semantic proximity Read ↗

Clinical Variant Databases and Machine Learning Prediction Supporting Genomic Medicine.Semantic proximity Read ↗

GWASdb v2: an update database for human genetic variants identified by genome-wide association studies.Semantic proximity Read ↗

PhD-SNPg: a webserver and lightweight tool for scoring single nucleotide variants.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.