Article
Sex-specific survival difference in association with HLA-DRB1∗04 following allogeneic haematopoietic stem cell transplantation for lymphoid malignancies.
Human immunology - 1 Jan 2018
Balassa Katalin, Andrikovics Hajnalka, Remenyi Peter, Batai Arpad, Szilvasi Aniko, Bors Andras, Kiss Katalin Piroska, Rajczy Katalin, Inotai Dora, Torbagyi Eva, Lengyel Lilla, Barta Aniko, Gopcsa Laszlo, Tordai Attila, Masszi Tamas
Abstract excerpt
The role of HLA system in allogeneic haematopoietic stem cell transplantation (allo-HSCT) outcome is unarguable. In this study we investigated association of HLA-A,-B and-DRB1 alleles with overall survival (OS) in 186 patients undergoing allo-HSCT for lymphoid malignancies. Analyses confirmed significantly better OS for HLA-DRB1∗04 carriers compared with non-carriers (p = 0.01). Survival benefit was confined to...
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