Management of gastrointestinal complications in hereditary transthyretin amyloidosis: a single-center experience over 40 years.

Abstract excerpt

INTRODUCTION: Hereditary transthyretin amyloidosis (ATTRm amyloidosis) is a rare disease caused by the deposition and accumulation of insoluble non-native transthyretin fibrils in the body. The disease inevitably results in widespread organ disruption, and poor life expectancy. The GI tract is one organ system vulnerable to disruption and, although the clinical presentation of the disease varies, GI involvement...

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