Article
Expanded subgenomic mRNA transcriptome and coding capacity of a nidovirus.
Proceedings of the National Academy of Sciences of the United States of America - 17 Oct 2017
Di Han, Madden Joseph C, Morantz Esther K, Tang Hsin-Yao, Graham Rachel L, Baric Ralph S, Brinton Margo A
Abstract excerpt
Members of the order Nidovirales express their structural protein ORFs from a nested set of 3' subgenomic mRNAs (sg mRNAs), and for most of these ORFs, a single genomic transcription regulatory sequence (TRS) was identified. Nine TRSs were previously reported for the arterivirus Simian hemorrhagic fever virus (SHFV). In the present study, which was facilitated by next-generation sequencing, 96 SHFV body TRSs were...
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