Article
Association of CDKN2A/CDKN2B with inflammatory bowel disease in Koreans.
Journal of gastroenterology and hepatology - 1 Apr 2018
Lee Ho-Su, Lee Soo Bin, Kim Byoung Mok, Hong Myunghee, Jung Seulgi, Hong Jeonghoon, Baek Jiwon, Han Buhm, Oh Seak Hee, Kim Kyung Mo, Park Sang Hyoung, Yang Suk-Kyun, Ye Byong Duk, Song Kyuyoung
Abstract excerpt
BACKGROUND AND AIM: CDKN2A/CDKN2B locus on 9p21 is reported to be associated with various diseases, including cancer and cardiovascular and inflammatory diseases. Significant downregulation of CDKN2B-AS1 in inflamed colon tissue of inflammatory bowel disease (IBD) cases was reported in Europeans. This study aimed to confirm the suggestive association of CDKN2A/CDKN2B with IBD identified in our recent genome-wide...
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