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Article

GRIN2A mutations in epilepsy-aphasia spectrum disorders.

Brain & development - 1 Mar 2018

Yang Xiaoling, Qian Ping, Xu Xiaojing, Liu Xiaoyan, Wu Xiru, Zhang Yuehua, Yang Zhixian

Abstract excerpt

OBJECTIVE: Epilepsy-aphasia spectrum (EAS) are a group of epilepsy syndromes denoting an association between epilepsy, speech disorders and the EEG signature of centrotemporal spikes. Mutations in the GRIN2A gene, encoding the NMDA glutamate receptor α2 subunit were reported in focal epilepsy with speech disorder. We aimed to explore the role of GRIN2A mutations in patients with centrotemporal spikes related...

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Identifiers

PMID: 29056244
DOI: 10.1016/j.braindev.2017.09.007

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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