Article
Conditional Function of Autoaggregative Protein Cah and Common cah Mutations in Shiga Toxin-Producing Escherichia coli.
Applied and environmental microbiology - 1 Jan 2018
Carter Michelle Qiu, Brandl Maria T, Kudva Indira T, Katani Robab, Moreau Matthew R, Kapur Vivek
Abstract excerpt
Cah is a calcium-binding autotransporter protein involved in autoaggregation and biofilm formation. Although cah is widespread in Shiga toxin-producing Escherichia coli (STEC), we detected mutations in cah at a frequency of 31.3% in this pathogen. In STEC O157:H7 supershedder strain SS17, a large deletion results in a smaller coding sequence, encoding a protein lacking the C-terminal 71 amino acids compared with...
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