Article
The association between a genetic risk score for allergy and the risk of developing allergies in childhood-Results of the WHISTLER cohort.
Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology - 1 Feb 2018
Arabkhazaeli Ali, Ahmadizar Fariba, Leusink Maarten, Arets Hubertus G M, Raaijmakers Jan A M, Uiterwaal Cuno S P M, van der Ent Cornelis K, Maitland-van der Zee Anke-Hilse, Vijverberg Susanne J H
Abstract excerpt
BACKGROUND: Several genetic variants have been associated with the susceptibility to allergic disease in adults, but it remains unclear whether these genetic variants are also associated with the onset of allergic disease early in life. The aim of this study was to develop a genetic risk score (GRS) for allergy based on findings in adults and study its predictive capacity for allergy in children. METHODS: A GRS...
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