Article
A structural model of flagellar filament switching across multiple bacterial species.
Nature communications - 16 Oct 2017
Wang Fengbin, Burrage Andrew M, Postel Sandra, Clark Reece E, Orlova Albina, Sundberg Eric J, Kearns Daniel B, Egelman Edward H
Abstract excerpt
The bacterial flagellar filament has long been studied to understand how a polymer composed of a single protein can switch between different supercoiled states with high cooperativity. Here we present near-atomic resolution cryo-EM structures for flagellar filaments from both Gram-positive Bacillus subtilis and Gram-negative Pseudomonas aeruginosa. Seven mutant flagellar filaments in B. subtilis and two in P....
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