Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic Complexity of Autosomal Dominant Polycystic Kidney and Liver Diseases.

Journal of the American Society of Nephrology : JASN - 1 Jan 2018

Cornec-Le Gall Emilie, Torres Vicente E, Harris Peter C

Abstract excerpt

Data indicate significant phenotypic and genotypic overlap, plus a common pathogenesis, between two groups of inherited disorders, autosomal dominant polycystic kidney diseases (ADPKD), a significant cause of ESRD, and autosomal dominant polycystic liver diseases (ADPLD), which result in significant PLD with minimal PKD. Eight genes have been associated with ADPKD (PKD1 and PKD2), ADPLD (PRKCSH, SEC63, LRP5,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cysts
Share to Glucosidases
Share to Glucosyltransferases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Liver Diseases

Share to Low Density Lipoprotein Receptor-Related Protein-5

Share to Polycystic Kidney, Autosomal Dominant

Share to SEC Translocation Channels

Share to TRPP Cation Channels

Source

Open in PubMed Open full text

Identifiers

PMID: 29038287
DOI: 10.1681/ASN.2017050483
PMCID: PMC5748917

Genes

PKD1
ALG8
GANAB
LRP5
PKD2
PRKCSH
SEC63

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic Complexity of Autosomal Dominant Polycystic Kidney and Liver Diseases.PMID 29038287Read ↗

Genetic Spectrum of Polycystic Kidney and Liver Diseases and the Resulting Phenotypes.Semantic proximity Read ↗

Insights into Autosomal Dominant Polycystic Kidney Disease from Genetic Studies.Semantic proximity Read ↗

Recent advances in the molecular diagnosis of polycystic kidney diseaseSemantic proximity Read ↗

Evolving role of genetic testing for the clinical management of autosomal dominant polycystic kidney disease.Semantic proximity Read ↗

Polycystic liver disease genes: Practical considerations for genetic testingSemantic proximity Read ↗

[Polycystic kidneys: Genetic testing and correct classification clinically and therapeutically of increasing significance].Semantic proximity Read ↗

Clinical profile of autosomal dominant polycystic liver disease.Semantic proximity Read ↗

Autosomal dominant polycystic kidney disease: genetics, mutations and microRNAs.Semantic proximity Read ↗

Isolated polycystic liver disease genes define effectors of polycystin-1 function.Semantic proximity Read ↗

Determinants of renal disease variability in ADPKD.Semantic proximity Read ↗

Genetics of polycystic liver diseasesSemantic proximity Read ↗

Practical genetics for autosomal dominant polycystic kidney disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.