Article
Genetic variations in the p11/tPA/BDNF pathway are associated with post stroke depression.
Journal of affective disorders - 15 Jan 2018
Liang Jinfeng, Yue Yingying, Jiang Haitang, Geng Deqin, Wang Jun, Lu Jianxin, Li Shenghua, Zhang Kezhong, Wu Aiqin, Yuan Yonggui
Abstract excerpt
BACKGROUND: The effects of BDNF on post stroke depression (PSD) may be influenced by genetic variations in intracellular signal transduction pathways, such as the p11/tPA/BDNF pathway. In this study, we aimed to determine the association of polymorphisms in candidate genes of the gene transduction pathway with PSD, as well as the effects of the interactions between genes in our Chinese sample. METHODS:...
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