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Article

Biclustered Independent Component Analysis for Complex Biomarker and Subtype Identification from Structural Magnetic Resonance Images in Schizophrenia

26 Sept 2017

Abstract excerpt

Clinical and cognitive symptoms domain based subtyping in schizophrenia has been critiqued due to the lack of neurobiological correlates and heterogeneity in symptom scores. We therefore present a novel data driven framework using biclustered independent component analysis (B-ICA) to detect subtypes from the reliable and stable gray matter concentration (GMC) of patients with schizophrenia (Sz). The developed...

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PMID: 29018368
DOI: 10.3389/fpsyt.2017.00179

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